SYNTHESIS AND X-RAY STRUCTURAL CHARACTERIZATION OF AN IRON(III) COMPLEX OF THE FLUOROQUINOLONE ANTIMICROBIAL CIPROFLOXACIN, [FE(CIP)(NTA)]3-CENTER-DOT-5H(2)O (NTA=NITRILOTRIACETATO)

Authors
WALLIS SC GAHAN LR CHARLES BG HAMBLEY TW
Citation
Sc. Wallis et al., SYNTHESIS AND X-RAY STRUCTURAL CHARACTERIZATION OF AN IRON(III) COMPLEX OF THE FLUOROQUINOLONE ANTIMICROBIAL CIPROFLOXACIN, [FE(CIP)(NTA)]3-CENTER-DOT-5H(2)O (NTA=NITRILOTRIACETATO), Polyhedron, 14(20-21), 1995, pp. 2835-2840
Citations number
46
Categorie Soggetti
Chemistry Inorganic & Nuclear",Crystallography
Journal title
Polyhedron → ACNP
ISSN journal
02775387
Volume
14
Issue
20-21
Year of publication
1995
Pages
2835 - 2840
Database
ISI
SICI code
0277-5387(1995)14:20-21<2835:SAXSCO>2.0.ZU;2-8
Abstract
Reaction of the fluoroquinolone antimicrobial ciprofloxacin (cip) with iron(III) in the presence of nitrilotriacetate (nta) results in the i solation of yellow crystals of the complex [Fe(cip)(nta)]3 . 5H(2)O. T he X-ray structural studies establish that, in the solid state, coordi nation of the iron(III) occurs through the keto and the carboxylic aci d oxygen of the ciprofloxacin ligand to form a six-membered ring.