Around one-third of travellers to endemic areas receive pre-travel typ
hoid vaccination, increasingly with the new parenteral vaccination Typ
him Vi (Merieux). More than 200 cases of Salmonella typhi and S. parat
yphi infection are imported into the UK each year. Despite the widespr
ead use of immunisation, non-specialist clinicians and the travelling
public do not appear to fully appreciate the limitations of currently
available vaccination. These limitations are not adequately highlighte
d in either the Green Book of Immunisation against Infectious Diseases
(HMSO, 1992) or the new handbook Health Information for Overseas Trav
el(HMSO, 1995) which are important sources of reference for clinicians
and practice nurses. This may delay consideration of diagnosis and pr
esentation for treatment in immunised travellers.