ANTITUMOR EFFECT OF JUZEN-TAIHO-TO, A KAMPO MEDICINE, FOR TRANSPLANTED MALIGNANT GLIOMA

Authors
TAKAHASHI H NAKAZAWA S
Citation
H. Takahashi et S. Nakazawa, ANTITUMOR EFFECT OF JUZEN-TAIHO-TO, A KAMPO MEDICINE, FOR TRANSPLANTED MALIGNANT GLIOMA, International journal of immunotherapy, 11(2), 1995, pp. 65-69
Citations number
11
Categorie Soggetti
Immunology
Journal title
International journal of immunotherapy → ACNP
ISSN journal
02559625
Volume
11
Issue
2
Year of publication
1995
Pages
65 - 69
Database
ISI
SICI code
0255-9625(1995)11:2<65:AEOJAK>2.0.ZU;2-D
Abstract
An investigation into the antitumour effect of Juzen-Taiho-To (TJ-48, a kampo medicine) was conducted on malignant glioma using xenogeneic a nd syngeneic tumour models. Both models were divided into a control di et group and a group receiving a TJ-48-supplemented diet, and the anti tumour effect and survival rate were compared. immune function paramet ers and tumour necrosis factor (TNF) activity were also serially measu red. Prolongation of survival was noted in the TJ-48 group as well as an increase of natural killer (NK) cell activity and TNF production.