SHORT-TERM QUINOLONES FOR SUCCESSFUL ERADICATION OF MULTIPLY RESISTANT VIBRIO-CHOLERAE IN ADULT PATIENTS

There has been an increasing multiple drug resistance problem in Vibri o cholerae biotype Eltor, the causative agent of 7th pandemic. The aim of this study was to show in vitro and in vivo susceptibility and eff ectiveness of quinolones in the treatment of endemic cholera cases. Ex cellent results were obtained in 53 bacteriologically confirmed choler a patients treated with short-term ofloxacin and ciprofloxacin. To our knowledge, there has been no previous report on this subject in the i nternational medical literature. Our results show that quinolones can be an alternative drug for the treatment of multiply resistant V. chol erae infections.