PULMONARY ADIASPIROMYCOSIS IN A 2-YEAR OLD GIRL

Citation
K. Nuorva et al., PULMONARY ADIASPIROMYCOSIS IN A 2-YEAR OLD GIRL, Journal of Clinical Pathology, 50(1), 1997, pp. 82-85
Citations number
11
Categorie Soggetti
Pathology
ISSN journal
00219746
Volume
50
Issue
1
Year of publication
1997
Pages
82 - 85
Database
ISI
SICI code
0021-9746(1997)50:1<82:PAIA2O>2.0.ZU;2-6
Abstract
A case of disseminated bilateral pulmonary adiaspiromycosis is reporte d in a two year old Finnish girl. She recovered from this rare infecti on after treatment with amphotericin B. She is the first human case of adiaspiromycosis in Scandinavia and she is the youngest child with th is disease reported so far. Electron microscopy showed that the three layers of the spore wall were not typical; rather, there seemed to be a gradual transition between the main wall. zones, which may be split into an indefinite number of thin layers. Varying numbers and thicknes ses were seen with different staining methods, and in different spores . Diagnosis relies on recognition of the fungus in a pulmonary biopsy specimen, because there are no reliable serological tests and culture of the fungus is time consuming and not always successful. It was thou ght that this patient had become infected as a result of contact with soil dust containing the spores in the yard surrounding her home, and as a result of her mother's work in a large garden shop.