A case of disseminated bilateral pulmonary adiaspiromycosis is reporte
d in a two year old Finnish girl. She recovered from this rare infecti
on after treatment with amphotericin B. She is the first human case of
adiaspiromycosis in Scandinavia and she is the youngest child with th
is disease reported so far. Electron microscopy showed that the three
layers of the spore wall were not typical; rather, there seemed to be
a gradual transition between the main wall. zones, which may be split
into an indefinite number of thin layers. Varying numbers and thicknes
ses were seen with different staining methods, and in different spores
. Diagnosis relies on recognition of the fungus in a pulmonary biopsy
specimen, because there are no reliable serological tests and culture
of the fungus is time consuming and not always successful. It was thou
ght that this patient had become infected as a result of contact with
soil dust containing the spores in the yard surrounding her home, and
as a result of her mother's work in a large garden shop.