DETECTION OF DEEP MYOMETRIAL INVASION IN ENDOMETRIAL CARCINOMA - COMPARISON OF TRANSVAGINAL ULTRASOUND, CT, AND MRI

Objective: The aim of this study was to compare the accuracy of transv aginal US (TVUS), CT, and MRI in detecting deep myometrial invasion in endometrial carcinoma. Materials and Methods: Twenty-six patients wit h endometrial carcinoma were evaluated with TVUS, CT, and MRI. The dep th of myometrial invasion was estimated in each examination. The invas ion depth was categorized into no/superficial and deep and was compare d to surgical and pathologic findings. Results: At pathologic examinat ion, the depth of myometrial invasion was no/superficial in 16 patient s and deep in 10. The accuracy/sensitivity/specificity of TVUS, CT, an d MRI in detecting deep myometrial invasion were 69/50/81, 61/40/75, a nd 89%/90%/88%, respectively. The sensitivity and accuracy of MRI in d etecting deep myometrial invasion were significantly higher than those of TVUS and CT (p = 0.049 for both sensitivity and accuracy). Conclus ion: We recommend MRI instead of CT or TVUS for the evaluation of the depth of myometrial invasion in endometrial carcinoma.