AMBLYOPIA - A TALE OF 2 APPROACHES

Our understanding of the physiological basis for amblyopia in humans h as undergone dramatic changes over the past two decades. The first suc h change occurred when we were first able to record from single neuron es in different parts of the visual pathway and develop neural models of the anomaly. The second came from psychophysical investigations and evaluations of these animal models. Our understanding has progressed from one focused on the properties of single cortical cells to an appr eciation of the anomalous behaviour of cellular networks.