UVEITIS - LATE COMPLICATION OF MISDIAGNOS ED WHIPPLES-DISEASE

We report a case of severe chronic bilateral uveitis in a 60-year old white man without neorulogical manifestations. Spondylarthritis and is olated malabsorption suggested the diagnosis of Whipple's disease. A n ormal duodenal biopsy delated the diagnosis, who was secondarly demons trated on adenopathy biopsy and macrophage study on vitrectomy sample (macrophage distended by periodic acid-Schiff positive material). With 1 year follow-up the uveitis was rapidly and completely cured by an a ntibiotic association (rifampicin and trimethoprim-sulfamethoxazol). T he characteristics of ocular involvement in Whipple's disease and trea tment of the disease are discussed.