Ai. Qureshi et al., PREDICTORS OF EARLY DETERIORATION AND MORTALITY IN BLACK-AMERICANS WITH SPONTANEOUS INTRACEREBRAL HEMORRHAGE, Stroke, 26(10), 1995, pp. 1764-1767
Background and Purpose Black Americans with spontaneous intracerebral
hemorrhage (SIGH) may have unique clinical characteristics that affect
outcome. The aim of this study was to determine the prognostic value
of clinical characteristics and initial CT scan for outcome in black A
mericans with SIGH. Methods Clinical and demographic data were extract
ed from the charts of 182 consecutive black Americans admitted for SIG
H diagnosed by clinical criteria and initial CT scan. Hemorrhage volum
es were calculated from admission CT scans by a computerized method. U
nivariate and multiple logistic regression analyses were performed to
determine independent predictors of early deterioration (defined as a
decrease from an initial Glasgow Coma Scale score >12 by greater than
or equal to 4 points within 24 hours from presentation) and mortality.
Results Both hemorrhage volume and ventricular extension were signifi
cant, independent predictors of early deterioration (odds ratio [OR],
6.78; 95% confidence interval [CI], 1.89 to 24.35 and OR, 4.67; 95% CI
, 1.30 to 16.72, respectively) and mortality (OR, 6.66; 95% CI, 2.85 t
o 15.58 and OR, 4.23; 95% CI, 1.82 to 9.82, respectively). A Glasgow C
oma Scale score less than or equal to 12 also predicted mortality (OR,
3.23; 95% CI, 1.46 to 7.14). Initial mean arterial pressure was not a
n independent predictor of early deterioration or mortality. Conclusio
ns Hemorrhage volume and ventricular extension are the best predictors
of early deterioration and mortality in black Americans with SICH.