Chagas disease is a tropical disease now making its appearance in the
United States as more immigration from Latin America occurs. Pregnant
women with chronic infection with Trypanosoma cruzi may present with c
ardiac or gastrointestinal symptoms and transmit the infection to thei
r fetuses. Case: A 32-year-old Mexican woman presented with cardiac sy
mptoms at 16 weeks' gestation. She was found to have a left anterior h
emiblock on her electrocardiogram. Her indirect immunofluorescent anti
body titer for T cruzi was positive at greater than 1:2048. Subsequent
ly, she had a normal pregnancy and delivery. The infant's T cruzi immu
nofluorescent antibody titer was 1:256 at birth and had not declined a
t his 6-week follow-up. Conclusion: Obstetric care providers in the Un
ited States need to be familiar with American trypanosomiasis because
it may present during pregnancy. Serious maternal disease is possible,
and perinatal transmission