RATJADON - A NEW ANTIFUNGAL COMPOUND FROM SORANGIUM-CELLULOSUM (MYXOBACTERIA) - PRODUCTION, PHYSICOCHEMICAL, AND BIOLOGICAL PROPERTIES

Authors
GERTH K SCHUMMER D HOFLE G IRSCHIK H REICHENBACH H
Citation
K. Gerth et al., RATJADON - A NEW ANTIFUNGAL COMPOUND FROM SORANGIUM-CELLULOSUM (MYXOBACTERIA) - PRODUCTION, PHYSICOCHEMICAL, AND BIOLOGICAL PROPERTIES, Journal of antibiotics, 48(9), 1995, pp. 973-976
Citations number
8
Categorie Soggetti
Pharmacology & Pharmacy",Immunology,"Biothechnology & Applied Migrobiology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
48
Issue
9
Year of publication
1995
Pages
973 - 976
Database
ISI
SICI code
0021-8820(1995)48:9<973:R-ANAC>2.0.ZU;2-I
Abstract
An antifungal activity, ratjadon, was detected in the culture broth of Sorangium cellulosum (Myxococcales) strain So ce360. The metabolite w as quantitatively bound to the adsorber resin XAD-16, which was added to the medium at the beginning of the fermentation. The antibiotic spe ctrum was narrow, but some important phytopathogenic fungi, especially species of Oomycetes, were inhibited at very low concentrations.