THE TREATMENT OF KELOIDS WITH INTRALESION AL BLEOMYCIN

Authors
Citation
I. Bodokh et P. Brun, THE TREATMENT OF KELOIDS WITH INTRALESION AL BLEOMYCIN, Annales de dermatologie et de venereologie, 123(12), 1996, pp. 791-794
Citations number
16
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
01519638
Volume
123
Issue
12
Year of publication
1996
Pages
791 - 794
Database
ISI
SICI code
0151-9638(1996)123:12<791:TTOKWI>2.0.ZU;2-E
Abstract
Introduction : Treatment of keloids is often disappointing and sometim e quite difficult to manage. In addition to unpleasent esthetic effect s, treatment may also produce functional impairment due to pruritis an d contraction of the scar tissue. Patients and methods: We proposed a new treatment scheme using intralesional infiltrations of bleomycin. R esults : We treated 31 keloids and 5 hypertrophic scars with 3 to 5 in filtrations within a 1-month period. Total regression was obtained in 25 keloids and hypertrophic scars. Important regression was obtained i n 6 keloids (86 % good results). Treatment was effective in all cases within the first 2 infiltrations evidenced by a reduction in the volum e of the kheloid and clear reduction of functional impairment in most patients. Conclusion: Effective well-tolerated treatment without pain was achieved with infiltration suggesting that this treatment should b e used as first line therapy for keloids.