Introduction : Treatment of keloids is often disappointing and sometim
e quite difficult to manage. In addition to unpleasent esthetic effect
s, treatment may also produce functional impairment due to pruritis an
d contraction of the scar tissue. Patients and methods: We proposed a
new treatment scheme using intralesional infiltrations of bleomycin. R
esults : We treated 31 keloids and 5 hypertrophic scars with 3 to 5 in
filtrations within a 1-month period. Total regression was obtained in
25 keloids and hypertrophic scars. Important regression was obtained i
n 6 keloids (86 % good results). Treatment was effective in all cases
within the first 2 infiltrations evidenced by a reduction in the volum
e of the kheloid and clear reduction of functional impairment in most
patients. Conclusion: Effective well-tolerated treatment without pain
was achieved with infiltration suggesting that this treatment should b
e used as first line therapy for keloids.