ENANTIOSELECTIVE REDUCTIONS OF PROCHIRAL KETONES BY MEANS OF OXAZABOROLIDINES

Authors
TARABA M PALECEK J
Citation
M. Taraba et J. Palecek, ENANTIOSELECTIVE REDUCTIONS OF PROCHIRAL KETONES BY MEANS OF OXAZABOROLIDINES, Chemicke listy, 91(1), 1997, pp. 9-22
Citations number
70
Categorie Soggetti
Chemistry
Journal title
Chemicke listy → ACNP
ISSN journal
00092770
Volume
91
Issue
1
Year of publication
1997
Pages
9 - 22
Database
ISI
SICI code
0009-2770(1997)91:1<9:EROPKB>2.0.ZU;2-V
Abstract
The possibilities of synthetic utilization of enantioselective reducti ons of prochiral ketones catalyzed by 1,2,3-oxazaborolidines are shown on a series of representative pattern reactions. The presented reacti ons are evaluated from the point of view of reaction conditions, i.e, type and amount of the used catalyst, reduction agent (BH3.THF, BH3.SM e(3), catecholborane), solvent (THF, toluene, CH2Cl2, i.a.) or activat or (simple alcohols or ethanolamine).