EVALUATION OF DIROFILARIA-IMMITIS EXCRETORY-SECRETORY PRODUCTS FOR SEROEPIDEMIOLOGICAL STUDIES ON HUMAN DIROFILARIASIS

Authors
SANTAMARIA B CORDERO M MURO A SIMON F
Citation
B. Santamaria et al., EVALUATION OF DIROFILARIA-IMMITIS EXCRETORY-SECRETORY PRODUCTS FOR SEROEPIDEMIOLOGICAL STUDIES ON HUMAN DIROFILARIASIS, Parasite, 2(3), 1995, pp. 269-273
Citations number
17
Categorie Soggetti
Parasitiology
Journal title
Parasite → ACNP
ISSN journal
1252607X
Volume
2
Issue
3
Year of publication
1995
Pages
269 - 273
Database
ISI
SICI code
1252-607X(1995)2:3<269:EODEPF>2.0.ZU;2-E
Abstract
The usefulness of excretory/secretory (E/S) products of adult Dirofila ria immitis for the diagnosis of human dirofilariosis was evaluated in 97 human sera using an ELISA and a Western Blot analysis with E/S ant igens. Results of the ELISA analysis show that in healthy individuals from an endemic area seropositivity is high (22%). Immune Blot analysi s shows that the reaction pattern with E/S antigens differentiates hea lthy seropositives, which recognize a 43 kDa band, from patients with pulmonary dirofilariosis, which specifically recognize bands between 2 2-28 kDa.