SERTRALINE 50 MG DAILY - THE OPTIMAL DOSE IN THE TREATMENT OF DEPRESSION

The dose regimen for sertraline in the treatment of depression has bee n well established. The starting dose, 50 mg/day, is the usually effec tive therapeutic dose, and the optimal dose when considering both effi cacy and tolerability for most patients, For patients who do not show an adequate therapeutic response within 2-4 weeks, the dose of sertral ine can be increased in 50 mg/day increments at no less than weekly in tervals to a maximum of 200 mg/day, Sertraline is generally given as a single daily dose and may be administered at any time of the day. In contrast to other selective serotonin reuptake inhibitors, there is no need for altered dose recommendations in the elderly.