COMBINED THERAPY IN A CASE OF MALIGNANT MESOTHELIOMA OF THE TUNICA VAGINALIS TESTIS

Malignant mesothelioma of the tunica vaginalis testis is exceedingly r are. A new case mimicking hydrocele in a 47-year-old man is here repor ted. Clinical staging revealed scrotal cutaneous and funicular tumor i nvasion together with retroperitoneal adenopathies. Once visceral diss emination was ruled out, radical orchiectomy, left hemiscrotectomy and modified retroperitoneal lymph node dissection were performed. Adjuva nt systemic chemotherapy and radiation were also administered. Histolo gically, an epithelial neoplasm with papillary pattern was evidenced. CAM 5.2 cytokeratin was positive in proliferating cells, but carcinoem bryonic and Leu M1 antigens gave negative results. Three years later t he patient is free of disease.