PREOVULATORY SONOGRAPHIC UTERINE RECEPTIVITY INDEX (SURI) - USEFULNESS AS AN INDICATOR OF PREGNANCY IN WOMEN UNDERGOING ASSISTED REPRODUCTIVE TREATMENTS

Citation
P. Serafini et al., PREOVULATORY SONOGRAPHIC UTERINE RECEPTIVITY INDEX (SURI) - USEFULNESS AS AN INDICATOR OF PREGNANCY IN WOMEN UNDERGOING ASSISTED REPRODUCTIVE TREATMENTS, Journal of ultrasound in medicine, 14(10), 1995, pp. 751-755
Citations number
22
Categorie Soggetti
Acoustics,"Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
02784297
Volume
14
Issue
10
Year of publication
1995
Pages
751 - 755
Database
ISI
SICI code
0278-4297(1995)14:10<751:PSURI(>2.0.ZU;2-9
Abstract
To evaluate the uterine component as a determinant variable in the pro bability of establishing a pregnancy after assisted reproductive treat ments, we introduced a mathematical formula derived from standard endo vaginal uterine monitored color Doppler imaging parameters. We analyze d 102 cycles of ovarian stimulation with leuprolide acetate and exogen ous gonadotropins resulting in 52 clinical pregnancies by stepwise log istic regression analysis. Sonographic endometrial pattern, thickness, diastolic blood flow, and resistive index variables were transformed into categorical variables and forced to yield a regression equation. Sonographic uterine receptivity index was calculated as a summation of four times endometrial pattern, five times resistive index, and two t imes diastolic blood flow. This index yielded values for each patient in a range of 0 to 15. Scores greater than or equal to 13 were associa ted with a successful outcome in 79.4% of the patients, whereas scores between 8 and 12 were accompanied by 45.8% pregnancy rates (P = 0.01) , and scores less than or equal to 7 had successful treatment outcome in only 7.7% (P = 0.0001). The scores obtained by this mathematical eq uation provide the ability to make reliable predictions about the outc ome of assisted reproductive treatments in women undergoing ovulation induction with leuprolide acetate and human menopausal gonadotropins.