STRAIGHTFORWARD SYNTHESIS OF OPTICALLY PURE METHYL (S)-2-PHTHALIMIDO-4-OXOBUTANOATE AND SOME OF ITS ACETAL AND THIOACETAL DERIVATIVES

Authors
MEFFRE P DURAND P LEGOFFIC F
Citation
P. Meffre et al., STRAIGHTFORWARD SYNTHESIS OF OPTICALLY PURE METHYL (S)-2-PHTHALIMIDO-4-OXOBUTANOATE AND SOME OF ITS ACETAL AND THIOACETAL DERIVATIVES, Synthesis, (9), 1995, pp. 1111
Citations number
38
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
9
Year of publication
1995
Database
ISI
SICI code
0039-7881(1995):9<1111:SSOOPM>2.0.ZU;2-W
Abstract
An improved procedure for the synthesis of optically pure methyl (S)-2 -phthalimido-4-oxobutanoate (3a) and some of its acetal and thioacetal derivatives 4, 5 and 7 from cheap commercially available L-methionine methyl ester hydrochloride (1a) is described.