CONVENIENT PREPARATION OF O-BENZYL-N-CBZ-D-SERINOL, AN INTERMEDIATE IN BETA-HYDROXY-ALPHA-AMINO ACID SYNTHESIS

Authors
DELLEMONACHE G DIGIOVANNI MC MAGGIO F MISITI D ZAPPIA G
Citation
G. Dellemonache et al., CONVENIENT PREPARATION OF O-BENZYL-N-CBZ-D-SERINOL, AN INTERMEDIATE IN BETA-HYDROXY-ALPHA-AMINO ACID SYNTHESIS, Synthesis, (9), 1995, pp. 1155
Citations number
41
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
9
Year of publication
1995
Database
ISI
SICI code
0039-7881(1995):9<1155:CPOOAI>2.0.ZU;2-V
Abstract
A convenient preparation of )-3-benzyloxy-2-[(benzyloxycarbonyl)amino] propanol (2) in 52% yield, employing cheap L-serine as starting materi al, is described. Conversion of 2 into methyl enzyloxy-4-[(benzyloxyca rbonyl)amino]pent-2-enoate (1) is reported.