This is a retrospective study involving 4708 consecutive appendix spec
imens removed over a period of 6.5 years for a clinical diagnosis of a
cute appendicitis, 64 (1.3%) of which showed histological evidence of
schistosomiasis. Thirty-four schistosomal appendicitis (SA) cases were
compared with 68 non-schistosomal appendicitis (NSA) cases admitted d
uring the same period. SA patients were older in age, usually of male
sex, mostly Egyptians acid tended to have a higher hemoglobin and a lo
wer leukocyte count (P<0.05). Other features were not significantly di
fferent. It is concluded that, despite these differences, there are no
reliable clinical or laboratory features by which SA can be predicted
preoperatively. The majority of the studied patients were either disc
harged before the results of the histopathology study were ready and w
ere lost to follow-up or the reports were overlooked. Therefore, we re
commend that for all post-appendectomy patients living in or coming fr
om endemic areas of schistosomiasis, the results of the histopathology
study should be processed as early as possible and before the patient
can be discharged so that the treatment can be commenced. Moreover, e
stablishing a system by which infected patients could be traced and he
nce treated is highly recommended.