THE STRUCTURE OF A NOVEL CEMBRANOID DITERPENE FROM A PHILIPPINE COLLECTION OF THE SOFT CORAL SINULARIA-FLEXIBILIS

Authors
GUERRERO PP READ RW BATLEY M JANAIRO GC
Citation
Pp. Guerrero et al., THE STRUCTURE OF A NOVEL CEMBRANOID DITERPENE FROM A PHILIPPINE COLLECTION OF THE SOFT CORAL SINULARIA-FLEXIBILIS, Journal of natural products, 58(8), 1995, pp. 1185-1191
Citations number
24
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
58
Issue
8
Year of publication
1995
Pages
1185 - 1191
Database
ISI
SICI code
0163-3864(1995)58:8<1185:TSOANC>2.0.ZU;2-A
Abstract
A new optically active diterpene lactone, sinulariolone [1], has been isolated as the major secondary metabolite in a Philippine collection of Sinularia flexibilis. The compound has a tricyclic structure and is more highly oxygenated than previously reported diterpenes from this species. The structure of 1 was elucidated by spectroscopy and its rel ative stereochemistry confirmed by single-crystal X-ray crystallograph y.