Pp. Guerrero et al., THE STRUCTURE OF A NOVEL CEMBRANOID DITERPENE FROM A PHILIPPINE COLLECTION OF THE SOFT CORAL SINULARIA-FLEXIBILIS, Journal of natural products, 58(8), 1995, pp. 1185-1191
A new optically active diterpene lactone, sinulariolone [1], has been
isolated as the major secondary metabolite in a Philippine collection
of Sinularia flexibilis. The compound has a tricyclic structure and is
more highly oxygenated than previously reported diterpenes from this
species. The structure of 1 was elucidated by spectroscopy and its rel
ative stereochemistry confirmed by single-crystal X-ray crystallograph
y.