A SHORT ENANTIOSELECTIVE SYNTHESIS OF A BIOLOGICALLY-ACTIVE COMPOUND FROM PERSEA-AMERICANA

Authors
MACLEOD JK SCHAFFELER L
Citation
Jk. Macleod et L. Schaffeler, A SHORT ENANTIOSELECTIVE SYNTHESIS OF A BIOLOGICALLY-ACTIVE COMPOUND FROM PERSEA-AMERICANA, Journal of natural products, 58(8), 1995, pp. 1270-1273
Citations number
10
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
58
Issue
8
Year of publication
1995
Pages
1270 - 1273
Database
ISI
SICI code
0163-3864(1995)58:8<1270:ASESOA>2.0.ZU;2-Y
Abstract
A short synthesis (12Z,15Z)-2-hydroxy-4-oxoheneicosa-12,15-dien-1-yl a cetate, a bioactive compound isolated from the avocado plant, Persea a mericana, has been achieved by an enantioselective aldol reaction of 2 -acetoxyacetaldehyde with (10Z,13Z)-nonadeca-10,13-dien-2-one.