Md. Stetter et al., HERPESVIRUS-ASSOCIATED MALIGNANT-LYMPHOMA IN A SLOW LORIS (NYCTICEBUSCOUCANG), Journal of zoo and wildlife medicine, 26(1), 1995, pp. 155-160
An Il-yr-old male captive slow loris, Nycticebus coucang, was examined
for an upper respiratory tract infection. Physical examination reveal
ed bilateral mucopurulent oculonasal discharge, severe dental disease,
mandibular lymphadenopathy, and increased pulmonary sounds. A complet
e blood count revealed severe lymphocytosis and neoplastic-appearing l
ymphocytes in the peripheral blood. A necropsy revealed marked hepatos
plenomegaly, mediastinal and submandibular lymphadenopathy, and pale,
firm lungs. Based on histopathology the diagnosis was lymphoma with in
volvement of the spleen, lymph nodes, lung, bone marrow, and conjuncti
va. A herpesvirus was identified by electron microscopy in cultured mo
nonuclear cells collected from whole blood samples.