The effect of propofol infusion on the stress response was studied in
patients undergoing coronary artery bypass graft (CABG) Ten patients r
eceived propofol infusion during cardiopulmonary bypass (CPBJ and ten
controls received diazepam. Blood levels of cortisol, adrenaline and n
oradrenaline were sampled. There was a significant reduction in all th
ree hormones(P< 0.05) in the study group. In addition, the amount of s
odium nitroprusside used during CPB was significantly reduced (P<0.05)
.