EFFECT OF PROPOFOL INFUSION ON THE ENDOCRINE RESPONSE TO CARDIAC-SURGERY

Citation
A. Ng et al., EFFECT OF PROPOFOL INFUSION ON THE ENDOCRINE RESPONSE TO CARDIAC-SURGERY, Anaesthesia and intensive care, 23(5), 1995, pp. 543-547
Citations number
16
Categorie Soggetti
Anesthesiology,"Emergency Medicine & Critical Care
ISSN journal
0310057X
Volume
23
Issue
5
Year of publication
1995
Pages
543 - 547
Database
ISI
SICI code
0310-057X(1995)23:5<543:EOPIOT>2.0.ZU;2-4
Abstract
The effect of propofol infusion on the stress response was studied in patients undergoing coronary artery bypass graft (CABG) Ten patients r eceived propofol infusion during cardiopulmonary bypass (CPBJ and ten controls received diazepam. Blood levels of cortisol, adrenaline and n oradrenaline were sampled. There was a significant reduction in all th ree hormones(P< 0.05) in the study group. In addition, the amount of s odium nitroprusside used during CPB was significantly reduced (P<0.05) .