Mh. Bogart et al., PRENATAL-DIAGNOSIS OF A STABLE DE-NOVO CENTRIC FISSION - A CASE-REPORT, American journal of medical genetics, 59(1), 1995, pp. 36-37
We report on the prenatal diagnosis of a baby with a de novo centromer
ic fission of chromosome 21. Both fission products were mitotically st
able. Follow-up chromosome analysis after birth confirmed the centrome
re fission. This chromosome fission appears to be without clinical sig
nificance for this patient. (C) 1995 Wiley-Liss, Inc.