Tj. Gao et al., MICROSCOPIC EVALUATION OF BONE-IMPLANT CONTACT BETWEEN HYDROXYAPATITE, BIOACTIVE GLASS AND TRICALCIUM PHOSPHATE IMPLANTED IN SHEEP DIAPHYSEAL DEFECTS, Biomaterials, 16(15), 1995, pp. 1175-1179
In order to compare morphological discrepancies in bone-implant contac
t in vertebrates, cylinders of hydroxyapatite, bioactive glass and tri
calcium phosphate were implanted in segmental defects of the tibia in
sheep. Three types of visible bone-implant contact were observed micro
scopically at 4 months after implantation, The trabecular web-like bon
e-implant contact noted in tricalcium phosphate seemed superior to the
disseminated patchy bone-implant contact in bioactive glass and the b
uttressed bone-implant contact in hydroxyapatite with respect to both
bone ingrowth and bioresorption of the implant. Differences of physico
chemical properties on the surface among the three kinds of bioceramic
implants probably give rise to different types of bone-implant contac
t.