SYNTHESIS OF TAXOIDS .1. REGIOSELECTIVE LEWIS ACID-MEDIATED RING-OPENING OF ARYL ORTHOACETATES

Authors
HARADA N HASHIYAMA T OZAKI K YAMAGUCHI T ANDO A TSUJIHARA K
Citation
N. Harada et al., SYNTHESIS OF TAXOIDS .1. REGIOSELECTIVE LEWIS ACID-MEDIATED RING-OPENING OF ARYL ORTHOACETATES, Heterocycles, 44, 1997, pp. 305-318
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
44
Year of publication
1997
Pages
305 - 318
Database
ISI
SICI code
0385-5414(1997)44:<305:SOT.RL>2.0.ZU;2-D
Abstract
The reaction of aryl orthoacetates with acetyl bromide readily proceed ed regioselectively to afford the desirable aryl bromides in the prese nce of tin(II) or zinc bromide as a catalyst. The synthesis of some do cetaxel derivatives is also described by using this improved process.