STRUCTURES OF 3 NEW DITERPENOIDS, FRITILLEBIC ACID AND FRITILLEBIN-A AND FRITILLEBIN-B, FROM BULBS OF FRITILLARIA-EBEIENSIS GD-YU ET GQ-JU

Authors
WU JZ MORIZANE C IIDA A UEDA S ZHOU ZL XU M ZHANG M LI RM FUJITA T
Citation
Jz. Wu et al., STRUCTURES OF 3 NEW DITERPENOIDS, FRITILLEBIC ACID AND FRITILLEBIN-A AND FRITILLEBIN-B, FROM BULBS OF FRITILLARIA-EBEIENSIS GD-YU ET GQ-JU, Chemical and Pharmaceutical Bulletin, 43(9), 1995, pp. 1448-1453
Citations number
20
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
43
Issue
9
Year of publication
1995
Pages
1448 - 1453
Database
ISI
SICI code
0009-2363(1995)43:9<1448:SO3NDF>2.0.ZU;2-K
Abstract
A new diterpenoid, fritillebic acid (1) and four new diterpenoid dimer s, fritillebins A (2) and B (3), and fritillebinides A and B, were iso lated from a crude drug, bulbs of Fritillaria ebeiensis G. D. YU et G. Q. JI. The structures of compounds 1-3 were determined to be ent-3 be ta-acetoxy-16 beta-kauran-17-oic acid (1), ent-16 beta-hydroxykauran-1 7-yl-ent-3 beta-acetoxg-16 beta-kauran-17-oate (2), and ent-3 beta-ace toxy-16 beta-hydroxykauran-17-yl ent-3 beta-acetoxy-16 beta-kauran-17- oate (3), respectively, on the basis of spectroscopic and chemical evi dence.