We consider in the paper the problem of the motion of a slightly defor
mable sphere embedded in a non-uniform potential flow-field. It is dem
onstrated that up to the first-order in the surface-deformation amplit
ude, the equations for the linear and angular velocities are uncoupled
. After deriving the dynamic equations by accounting for the small sur
face deformations, we treat the phenomenon of the body's self-propulsi
on and point out to a qualitative difference between the self-propulsi
on of a deformable sphere in a quiescent or uniform surrounding and, t
hat in a non-uniform ambient flow-field. The effect is more significan
t (by an order of magnitude) in the latter case. Also discussed is the
corresponding parametric resonant interaction as a possible mechanism
for self-propulsion.