Al. Ghindilis et al., A NEW SENSITIVE AND SIMPLE METHOD FOR DETECTION OF CATECHOLAMINES FROM ADRENAL CHROMAFFIN CELLS, Die Pharmazie, 50(9), 1995, pp. 599-600
A biosensor was used for the analysis of catecholamines in media and l
ysates of cultured bovine adrenal chromaffin cells, The sensor is comp
osed of coimmobilised laccase and glucose dehydrogenase coupled with a
n oxygen electrode, using the catalytic effect of cate cholamines for
glucose oxidation in this system, The analysis time is almost 5 min. T
he correlation between the biosensor and HPLC determination is 0.99.