Objective: To present our experience with mediastinal parathyroid cyst
s and summarize previously reported cases. Design: We retrospectively
reviewed medical records and reviewed the pertinent literature. Materi
al and Methods: The clinical, operative, and pathologic findings in 7
cases of mediastinal parathyroid cysts encountered at one institution
and 31 cases previously reported in the literature are described. Resu
lts: Rarely, cysts may arise from an aberrant mediastinal parathyroid
gland, Such cysts may manifest as a symptomatic mass, as an asymptomat
ic finding on roentgenography, or during the assessment of a patient w
ith hyperparathyroidism, The diagnosis may be made by fine-needle aspi
ration or by excision and pathologic examination. Conclusion: Function
ing parathyroid cysts represent degeneration of a hyperfunctioning gla
nd, such as an adenoma, and are usually removed through a cervical app
roach, Nonfunctioning cysts in asymptomatic patients with normal serum
calcium levels are considered indeterminate and should be managed acc
ordingly, Excision is usually recommended.