We interviewed 542 women whose mothers were in a randomized trial of d
iethylstilbestrol. Effects of diethylstilbestrol on the third generati
on were explored by ascertaining age at menarche for the women's daugh
ters. A total of 123 daughters were greater than or equal to 10 years
old (52 exposed and 71 unexposed). Age at menarche was unaffected by m
other's prenatal diethylstilbestrol exposure.