In this paper the research focus is on 'counterfactual' cases of growt
h-oriented SMEs in peripheral regions of Britain (Scotland, Northern E
ngland, Wales and Merseyside). These firms are systematically compared
to three control groups, made up of growth-oriented SMEs in the South
East, slow-growth firms in the Periphery, and slow-growth firms in th
e South East. Apart from some performance measures such as profits and
exports, three key characteristics of the firms are analysed. These a
re the extent of competition in the markets served, levels of innovati
on and R & D, and work force and labour market characteristics. The an
alysis is conducted for manufacturing firms and professional and busin
ess services separately. Firms of the research group stand out against
the other firms in the sample as businesses with a very favourable R
& D input-output ratio and greater propensity for providing a combinat
ion of formal internal and external training programmes. Possible expl
anations for these findings are suggested. The results provide conside
rable grounds for questioning the strong link between firm and environ
ment implied by regional development theory and for greater emphasis o
n the ways in which organizations may counteract and overcome comparat
ive environmental disadvantages.