Vp. Carnielli et al., EFFECT OF DIETARY TRIACYLGLYCEROL FATTY-ACID POSITIONAL DISTRIBUTION ON PLASMA-LIPID CLASSES AND THEIR FATTY-ACID COMPOSITION IN PRETERM INFANTS, The American journal of clinical nutrition, 62(4), 1995, pp. 776-781
Seven premature infants were each fed, for 1 wk in a crossover design.
The beta formula contained triacylglycerols resembling the stereoisom
eric structure of human milk fat (25.4% by wt 16:0, 76.1% of which is
at the sn-2 position), whereas in the ct formula 87.3% of total 16:0 (
25.7% by wt was at the sn-1,3 positions. Plasma lipids and their fatty
acid compositions were determined at the end of each 1 wk study perio
d. Infants fed with the beta formula had higher percentages of palmiti
c acid in plasma sterol esters, triacylglycerols, and free fatty acids
, and lower linoleic acid in triacylglycerols than with the cu formula
. Premature infants fed formulas with triacylglycerols 16:0 predominan
tly in the sn-2 rather than the sn-1,3 positions had alterations in th
eir plasma fatty acids consistent with enhanced absorption of 16:0 fro
m the sn-2 compared with the sn-1,3 positions.