The data obtained on red cell hemolysates from 16 patients with Hodgki
n's disease varying in age, sex, the disease stage and histology, time
since the diagnosis served tile basis for comparative evaluation of e
ndogenic intraerythrocytic hemoglobin proteolysis and relevant product
s. The results show that Hodgkin's disease brings about a 10-15-fold i
ncrease in the quantity of accumulated hemoglobin alpha-chain fragment
s.