SANDOSTATIN TREATMENT OF DIARRHEA VARYING IN GENESIS

Antidiarrheal action of sandostatin (octreotide) was studied in dumpin g syndrome, diabetic enteropathy, short-bowel syndrome, Crohn's diseas e and ulcerative colitis. Sandostatin proved effective in diarrhea of secretory, motor and osmotic orgin. Dumping syndrome, diabetic enterop athy, Crohn's disease and short-bowel syndrome responded completely. I n ulcerative colitis the effect was paradoxical: intensive diarrhea di scontinued, but moderate diarrhea became more intensive. Sandostatin i ndications in ulcerative colitis should receive further investigations .