DETERMINATION OF STRYCHNINE AND BRUCINE BY CAPILLARY ZONE ELECTROPHORESIS

Authors
ZONG YY CHE CT
Citation
Yy. Zong et Ct. Che, DETERMINATION OF STRYCHNINE AND BRUCINE BY CAPILLARY ZONE ELECTROPHORESIS, Planta medica, 61(5), 1995, pp. 456-458
Citations number
31
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
61
Issue
5
Year of publication
1995
Pages
456 - 458
Database
ISI
SICI code
0032-0943(1995)61:5<456:DOSABB>2.0.ZU;2-3
Abstract
A procedure for quantitative estimation of strychnine and brucine in t he extracts of Strychnos nux-vomica seeds by capillary zone electropho resis (CZE) was developed. The buffer solution used was 10mM phosphate buffer-MeOH (9:1), pH 2.5. The linear calibration range was 0.01-0.15 mg/ml. This method is useful for the qualitative and quantitative det ermination of strychnine and brucine in plant drug samples, as well I as in human plasma.