EFFECTS OF CATECHINS ON THE MOUSE-TUMOR CELL-ADHESION TO FIBRONECTIN

Authors
OGATA K MUKAE N SUZUKI Y SATOH K NARUMI K NUKIWA T ISEMURA M
Citation
K. Ogata et al., EFFECTS OF CATECHINS ON THE MOUSE-TUMOR CELL-ADHESION TO FIBRONECTIN, Planta medica, 61(5), 1995, pp. 472-474
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
61
Issue
5
Year of publication
1995
Pages
472 - 474
Database
ISI
SICI code
0032-0943(1995)61:5<472:EOCOTM>2.0.ZU;2-Y
Abstract
We studied the effects of 5 kinds of catechins on the adhesion of mous e lung carcinoma 3LL and melanoma B16F10 cells to the fibronectin subs tratum. (-)-Epicatechin gallate and (-)-epigallocatechin gallate were active in inhibiting the 3LL cell adhesion, while (+)-catechin, (-)-ep icatechin, and (-)-epigallocatechin were inactive. Gallate-containing catechins also impaired adhesion and/or spreading of B16F10 cells.