This article reviews established as well as emerging fields in the app
lication of transesophageal echocardiography (TEE) in, the investigati
on of myocardial ischemia. TEE already has a well defined and establis
hed role in, stress echocardiography in patients with poor transthorac
ic acoustic window, and in the detection of intraoperative myocardial
ischemia in cardiac and noncardiac surgery. The evaluation of right ve
ntricular ischemia and infarction. and the assessment of coronary flow
reserve (CFR) are relatively new fields in the application of TEE and
the potential of this technique has not yet been fully evaluated. The
evidence collected and reviewed in. this article is still preliminary
but it presupposes a significant role of TEE in, the diagnosis and pa
thophysiological assessment of myocardial ischemia.