A new group of clinical isolates of Campylobacter rectus has been isol
ated, which in liquid culture form a biofilm on the walls of glass and
polystyrene culture vessels, yet are highly motile when removed as cl
umps or single cells from the substratum. A free-swimming variant of s
uch a sticky variant has been selected. However, no differences (other
than behavioural) were detected between sticky and free-swimming form
s by Western immunoblotting with various patient sera or by enzyme act
ivity tests. Both expressed a dominant protein of c. 150 kDa, a major
component of the S-layer, which is lost in many laboratory lines of C,
rectus. Alteration between sessile and motile growth modes may expand
the habitat range of this proposed periodontopathogen.