Attentional modulation of cortical activity was examined by varying th
e rate of visual stimuli in object categorization tasks according to s
ingle and conjoined features. Activation of dorsolateral frontal corte
x was independent of the stimulus presentation rate and elicited by th
e participant's attention to conjoined compared with single features.
Several cortical regions showed attentionally modulated activity. In i
nferior temporal cortex, modulation was due to an additional bias sign
al underlying normal rate-correlated activity, In two other regions (p
remotor cortex and cerebellum), attention modified the correlation of
activity and the stimulus presentation rate, Attentional effects in th
e human cortex are expressed by at least two physiologically distinct
mechanisms acting on spatially distributed areas.