SYNTHESIS AND STRUCTURE OF 6-CHLORO-2,3-TRIMETHYLENE-4-PHENYLQUINOLINE

An X-ray structural investigation of 6-chloro-2,3-trimethylene-4-pheny lquinoline obtained by the reaction of 2-amino-5-chlorobenzophenone wi th cyclopentanone was carried out. At 20 degrees C, a = 23.750, b = 9. 242, c = 14.018 Angstrom, beta = 112.68 degrees, space group C2/c, Z = 8, 2647 reflections, R = 0.047. The five-membered ring has an envelop e conformation. Conjugation between the quinoline fragment and the phe nyl substituent is significantly distorted due to the rotation of the latter by -62.9 degrees.