Vm. Blinov et al., STRUCTURAL-FUNCTIONAL ORGANIZATION OF SMALLPOX VIRUS GENOME .4. SEQUENCING AND ANALYSIS OF THE RIGHT-HAND END OF STRAIN INDIA-1967, Molecular biology, 29(4), 1995, pp. 442-452
The right-hand terminal DNA segment (53,018 bp) of the variola(smallpo
x) virus strain India-1967 was sequenced. Computer analysis revealed 5
9 open reading frames; the genome region examined had multiple differe
nces from those of vaccinia virus strains Copenhagen and Western Reser
ve, but was highly homologous to variola virus strain Harvey. The puta
tive functions of viral proteins and the possible influence of the rev
ealed differences on the orthopoxvirus properties are discussed.