According to the measurement of the pigment production and some materi
al balance treatments, the monosodium glutamate (MSG), which represent
s a main substrate involved in the production of red pigment by Monasc
us ruber, is recovered on-line. Fedbatch operation then represents an
alternative for increasing the production of pigment. A nonlinear quot
ient control scheme is expressed to regulate the monosodium glutamate
substrate at an optimal value determined from batch studies.