CONTROL OF GASTRIC-ACID WITH HIGH-DOSE H2-RECEPTOR ANTAGONISTS AFTER OMEPRAZOLE FAILURE - REPORT OF 2 CASES

Authors
LEITE LP JUST RJ CASTELL DO LAGERSTROM PO
Citation
Lp. Leite et al., CONTROL OF GASTRIC-ACID WITH HIGH-DOSE H2-RECEPTOR ANTAGONISTS AFTER OMEPRAZOLE FAILURE - REPORT OF 2 CASES, The American journal of gastroenterology, 90(10), 1995, pp. 1874-1877
Citations number
27
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
The American journal of gastroenterology → ACNP
ISSN journal
00029270
Volume
90
Issue
10
Year of publication
1995
Pages
1874 - 1877
Database
ISI
SICI code
0002-9270(1995)90:10<1874:COGWHH>2.0.ZU;2-Y
Abstract
Successful omeprazole therapy in patients with symptomatic gastroesoph ageal reflux (GER) refractory to treatment with H2-receptor antagonist s has often been reported. In contrast, successful treatment of GER by H2-receptor antagonists in patients resistant to the acid-suppressing effects of omeprazole is rarely reported. We describe two patients wh o demonstrated therapeutic responses to high dose H2-receptor antagoni sts after high dose omeprazole failed to suppress gastric acidity and GER.