O. Marrone et al., RESPIRATION IN NREM AND REM-SLEEP AFTER UPPER AIRWAY SURGERY FOR OBSTRUCTIVE SLEEP-APNEA, Journal of sleep research, 4(3), 1995, pp. 189-195
To verify whether upper airway surgery in obstructive sleep apnoea syn
drome affects differently respiration in NREM and REM sleep, 22 patien
ts were studied by polysomnography before and three months after surgi
cal treatment. On the average, treatment improved respiration during b
oth deep states, but no significant interaction was found between slee
p state and effect of surgical treatment. According to the response to
treatment, three groups of patients were identified: the first group
(N = 6), with an improvement in apnoea-hypopnoea index (AHI), percenta
ge of sleep time spent in apnoea and hypopnoea (time in AH) and mean o
xyhaemoglobin saturation (SaO(2)) in both NREM and REM sleep; the seco
nd group (N = 5), with an improvement in AHI only in NREM sleep, assoc
iated with improvement in mean SaO(2) in both sleep states; the third
group (N = 11), without any improvement in AHI and time in AH, either
associated (N = 5) or not (N = 6) with an improvement in mean SaO(2) i
n both sleep states. An increase in the percentage of hypopnoeas out o
f the total AHI after treatment could partly account for the apparent
discrepancy between AHI and mean SaO(2) behaviour in the subjects of t
he second group, but not in the patients of the third group who improv
ed their mean SaO(2), Mixed apnoeas occurred before surgery in six sub
jects; they remained numerous after surgery only in two subjects who d
id not show any SaO(2) improvement, In conclusion, the degree of impro
vement in respiration after upper airway surgery was similar in every
patient in NREM and REM sleep.