L. Theret et al., ABOUT THE USE OF CLOZAPINE IN CHALONS-SUR -MARNE PSYCHIATRIC-HOSPITAL- INTESTINAL DILATATIONS WITH CLOZAPINE THERAPY, Annales medico-psychologiques, 153(7), 1995, pp. 474-477
The authors report three eases - one of them lethal - of intestinal oc
clusion among 30 patients tp eated with clozapine between 1991 and 199
4 in Chalons-sur-Marne Psychiatric Hospital. The responsability of clo
zapine seems to be linked with its potent anticholinergic property. Th
e attention of prescriptors is necessary and the monitoring of the dru
g should not be limited to the hematologic aspect.