D-PENICILLAMINE AND GOLD SALT TREATMENTS WERE COMPLICATED BY MYASTHENIA AND PEMPHIGUS, RESPECTIVELY, IN THE SAME PATIENT WITH RHEUMATOID-ARTHRITIS

Authors
CIOMPI ML MARCHETTI G BAZZICHI L PUCCETTI L AGELLI M
Citation
Ml. Ciompi et al., D-PENICILLAMINE AND GOLD SALT TREATMENTS WERE COMPLICATED BY MYASTHENIA AND PEMPHIGUS, RESPECTIVELY, IN THE SAME PATIENT WITH RHEUMATOID-ARTHRITIS, Rheumatology international, 15(3), 1995, pp. 95-97
Citations number
16
Categorie Soggetti
Rheumatology
Journal title
Rheumatology international → ACNP
ISSN journal
01728172
Volume
15
Issue
3
Year of publication
1995
Pages
95 - 97
Database
ISI
SICI code
0172-8172(1995)15:3<95:DAGSTW>2.0.ZU;2-G
Abstract
A 53-year-old woman with rheumatoid arthritis developed myasthenia gra vis after 6 months of therapy with D-penicillamine. Nineteen months af ter D-penicillamine was discontinued and 12 months after the beginning of gold therapy, she developed pemphigus vulgaris. This is the first reported case of gold-induced pemphigus in rheumatoid arthritis. This study further underlines the complex interactions between the effects of treatment with sulfhydryl-disulfide exchange drugs and the altered immunological system of patients affected by rheumatoid arthritis.