Jp. Begue et al., SYNTHESIS OF ALLYLIC TRIFLUOROMETHYL ALCOHOLS FROM 1-TRIFLUOROMETHYL-EPOXY ETHERS, Journal of fluorine chemistry, 80(1), 1996, pp. 13-16
alpha-Thiophenyl ketones are easily available by the regioselective ri
ng-opening of 1-trifluoromethyl-epoxy ethers with phenyl sodium thiola
te. Their in situ reduction with NaBH4, followed by oxidation with NaI
O4 and thermal decomposition of the resultant sulphoxides, provided al
lylic trifluoromethyl alcohols in high overall yield.