CHARACTERIZATION OF GROUP-A STREPTOCOCCI ISOLATED IN KUALA-LUMPUR, MALAYSIA

T-agglutination patterns of 190 strains of group A streptococci isolat ed between January 1989 and December 1993 from body fluids (10), throa t culture (56), pus (51) and skin lesions (73) were determined. Mucoid colonial morphology was exhibited by 6.3% (12/190) of the strains on initial isolation. Type T-5,11,27,44 comprised 23.7%, followed by T-1, 3,13,B3264 (11.1%), T-4,6 (8.4%) and T-8,25, Imp 19 (7.9%). About 42% (80/190) strains could not be characterized by T agglutination pattern . T-typing of 71 selected strains at WHO Collaborating Center, Minneap olis yielded similar results. Nineteen selected strains were further c haracterized by M-typing; only three strains were M-typeable. These st rains were isolated from throat (M1), sputum (M5) and pus (M12). About 68% (48/71) isolates produced serum opacity factor. These data suppor t the existence of as yet uncharacterized group A streptococcal seroty pes in this region.